According to a source close to Joystiq, BioWare's big announcement at the 2010 VGAs will be Mass Effect 3. But that's not all, they also disclosed that Mass Effect 3 will be seeing a first for the franchise - multiplayer.
This isn't too surprisingly, as EA recently said that they feel that single-player only experiences are on the way out.
We'll find out for sure whether Joystiq's source can really be trusted when the VGAs air at 1am GMT on the 12th of December. Be there, or be square.